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The Blood-Brain Barrier Labs

We study neurovascular function and its role in brain disease

Who We Are

We are a team of neuroscientists, clinicians, engineers, computer scientists, chemists, and mathematicians, working together to study the blood-brain barrier and its interactions with components of the neurovascular unit. The Blood-Brain Barrier labs are located at: Dalhousie University, Halifax and Ben-Gurion University of the Negev, Beer-Sheva but we are one team

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What We Study

The Blood-Brain Barrier (BBB) is a unique anatomical and physiological interface between the circulation system and the central nervous system (CNS), designed to maintain homeostasis within the extravascular-extracellular brain environment and preserve normal brain functioning.

We study the role of the neurovascular unit and BBB integrity of the normal brain and in the pathogenesis of brain disorders such as:

  • stroke

  • epilepsy

  • brain trauma

  • psychiatric disorders

  • neurodegenerative diseases

Our labs are multi-disciplinary, combining pre-clinical research in experimental models of brain diseases and clinical studies using brain imaging techniques in patients. We use a variety of methodologies including neurophysiological recordings, intravital microscopy and magnetic resonance imaging, histopathology, and molecular biology. We develop new approaches for the identification of brain and retinal damage for early disease detection, intervention, and follow-up treatment efficacy. 

The Friedman Lab Best Presentation at "Tomorrow: State of Mind" Conference 

"Breaking Barriers: From a Diseased to Healthy Brain"

Recent News

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Friedman Team Visit to Zambia
Friedman Team Visit to Zambia
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Invitation for those affected by war in Ukraine
Invitation for those affected by war in Ukraine
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Remembering George Somjen
Remembering George Somjen

February 2022

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Awarded CIHR Grant
Awarded CIHR Grant

February 2022

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New Publication!
New Publication!

December 2021

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Lab Retreat at Mitzpe Ramon
Lab Retreat at Mitzpe Ramon

December 2021

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Our Inspiration

A Legacy of
Support

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A Legacy of
Teaching

A Legacy of

Scientific Enthusiasm

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